1.0Andreas Kalckerhttps://kalcker.org/en/andreasKalckerWqhttps://kalcker.org/en/author/andreaskalckerwq/rich600338<blockquote class="wp-embedded-content" data-secret="WZ1syu1oQn"><a href="https://kalcker.org/en/coronavirus/">Coronavirus – EN</a></blockquote><iframe sandbox="allow-scripts" security="restricted" src="https://kalcker.org/en/coronavirus/embed/#?secret=WZ1syu1oQn" width="600" height="338" title="“Coronavirus – EN” — Andreas Kalcker" data-secret="WZ1syu1oQn" frameborder="0" marginwidth="0" marginheight="0" scrolling="no" class="wp-embedded-content"></iframe><script> /*! 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INTRODUCTION 1.1. Background 1.2. A brief summary on chlorine dioxide 1.3. Key points for reflection 1.4. What is Chlorine Dioxide Solution (CDS) and what are the differences with the Miracle Mineral Solution (MMS)? The unnecessary controversy and its consequences 2. EFFECTIVENESS, SAFETY AND TOXICITY OF CHLORINE DIOXIDE 2.1. Action against viruses 2.2. Pre-clinical studies 2.3. Clinical studies 2.4. Toxicity 3. RECOMMENDATIONS, PRECAUTIONS AND CONTRAINDICATIONS FOLLOWING MEDICAL EXPERIENCE 4. LEGAL FACTS AND INTERNATIONAL HUMAN RIGHTS 5. FINAL CONSIDERATIONS 6.REFERENCES 7.ANNEXES ACCOUNT FROM EXPERIENCE: THE BOLIVIAN CASE The Covid-19 pandemic shocked the world and has claimed many thousands of lives, and as one of the equally complicated consequences, the world economy was compromised. Undoubtedly, this is a problem that required an urgent solution and the commitment of everyone, especially health personnel, in the search for its prompt solution.   In order to identify a solution to this problem and also based on the scientific evidence already published and clinical experiences of use of chlorine dioxide (ClO₂) by physicians and researchers, we made an assessment of the main information to support our proposal for the use of chlorine dioxide solution (CDS), following the protocol standardized by Dr.h.c. Andreas Ludwig Kalcker as a safe and effective alternative to combat infection by SARS-COV2.   A review survey on the use of chlorine dioxide in the indexed international literature was carried out from January to July 2020 and as an example, if we analyzed only the PubMed website (National Library of Medicine 2020), we observe that only using the descriptor “chlorine dioxide”, we have available a total of 1,372 documents dating from 1933 to the research date, 2020 (Figure 1). 1.1 BACKGROUND Figure 1 – Number of documents found with the descriptor “chlorine dioxide” in the PubMed scientific database. The first red arrow indicates the descriptor used for the search and the second the number of published documents. Source: https://pubmed.ncbi.nlm.nih.gov/?term=chlorine+dioxide&sort=pubdate. Access date: 07/24/2020. Another important source was the PubChem database (Figure 2), in which it is also possible to identify biochemical and toxicological information, among others, and registered patents (which can also be found in Google Patents), among which the following stand out: 1) The patent on the disinfection of blood bags (Kross & Scheer, 1991); 2) The patent on HIV (Kuhne 1993); 3) The patent on the treatment of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease and multiple sclerosis (McGrath MS 2011); 4) Taiko Pharmaceutical’s patent (2008) for human coronavirus; 5) the patent on um method and composition “for treating cancerous tumors” for treating cancerous tumors (Alliger 2018); 6) the patent on pharmaceutical composition for treating internal inflammation (Kalcker LA, 2017); 7) the patent on pharmaceutical composition for the treatment of acute intoxication (Kalcker LA, 2017) and;8) the patent on a pharmaceutical compound for the treatment of infectious diseases (Kalcker LA, 2017);9) the patent on the use of CDS for coronavirus type 2 (Kalcker LA, 2020 – still pending publication: /11136-CH_Antrag_auf_Patenterteilung.pdf). Figure 2 – Number of documents found with the descriptor “chlorine dioxide” in the PubChem scientific database. The first red arrow indicates the descriptor used for the search and the second the number of documents published. Source: https://pubchem.ncbi.nlm.nih.gov/#query=chlorine%20dioxide Date of access: 24/07/2020. Therefore, with these initial data alone, we note that research on ClO₂ is nothing new, that it is a chemical molecule already known for more than 200 years and marketed for 100 years with various uses: treatment of water for human consumption, treatment of contaminated water, for biofilm control in cooling towers and in the processing of food and vegetable disinfection. In addition, since 40 years there are clinical and clinical studies conducted, as well as studies that allow us to understand its toxicological and safety characteristics especially for human use (Lubbers et al 1984, Ma et al 2017). 1.2. A BRIEF SUMMARY OF CHLORINE DIOXIDE The chemical formula of chlorine dioxide is ClO₂ and according to the Chemical Abstracts Services (CAS) from Chemical American Society its CAS number is 10049-04-4. In this formula, it is clear that there is one chlorine atom (Cl) and two oxygen atoms (O₂) in a chlorine dioxide molecule. These 3 atoms are held together by electrons to form the ClO₂ molecule. It can be used as a saturated gas in distilled water and can therefore be drunk or applied directly to the skin and mucous membranes, with appropriate dilutions. Andreas Ludwig Kalcker, Biophysicist and Researcher, standardized a saturation of the gas in distilled water called chlorine dioxide solution or CDS (National Library of Medicine 2020). The discovery of the ClO₂ molecule in 1814 is attributed to the scientist Sir Humphrey Davy. ClO₂ is different from the element chlorine (Cl), both in its chemical and molecular structure, as well as in its behavior. ClO₂, as has already been widely reported, can have toxic effects if the necessary care is not observed for its various uses and the appropriate recommendations for human consumption are not respected. It is more than well known that clo2gas is toxic to humans if inhaled pure and/or ingested in quantities higher than recommended (Lenntech 2020, IFA 2020). ClO₂ is one of the most effective biocides against pathogens such as bacteria, fungi, viruses, biofilms and other species of microorganisms that can cause disease. It acts by disrupting the synthesis of the pathogen’s cell wall proteins. As it is a selective oxidant, its mode of action is very similar to phagocytosis, where a mild oxidation process is used to eliminate all types of pathogens (Noszticzius et al 2013, Lenntech 2020). It is worth saying that ClO₂, generated by sodium chlorite (NaClO₂), is approved by the Environmental Protection Agency in the United States (EPA 2002) and by the World Health Organization for use in water fit for human consumption, as it leaves no toxic residues (EPA 2000, WHO 2002). When applied at appropriate concentrations, ClO₂ does not form any halogenated products and its residual ClO₂ by-products are normally within the limits recommended by EPA (2000, 2004) and ... Read morehttps://kalcker.org/wp-content/uploads/2023/10/cuidados.jpg